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The news about Insulet’s updated algorithm and new lower target of 100 mg/dL is very significant and something I am very excited about. The Omnipod 5 appeals to many people with diabetes because it’s the only tubeless automated insulin delivery system. It’s generally easier to wear compared to tubed pumps and easier to fill and start. Lower targets typically yield more time in range, and as other pumps, such as the MiniMed 780G (Medtronic) and Twiist (Sequel) now offer lower targets. Having the option to go lower is very desirable, especially in adults.
The other component I am especially excited about is less automated insulin delivery interruptions, especially when reaching the maximum insulin delivery. Most patients do very well with this system, but some struggle, often related to forgetting to bolus or not having optimized carbohydrate ratios. This can lead to a limited mode, which does not allow for the dynamic insulin delivery, and often leads to more sustained highs unless the person takes immediate action. With the update, users will be advised to check glucose when this occurs, but they will stay in automated mode.
I believe these updated features will be very helpful for my patients. I also do a lot of management in pregnancy and although this system is off label for pregnancy, many women prefer to continue to use it while pregnant and I believe the lower target will be very beneficial.
Diana Isaacs, PharmD, BCPS, BCACP, BC-ADM, CDCES, FADCES, FCCP
Healio | Endocrine Today Editorial Board Member
Endocrine Clinical Pharmacy Specialist
Co-Director, Endocrine Disorders in Pregnancy
Cleveland Clinic Endocrinology & Metabolism Institute
Disclosures: Isaacs reports speaking or consulting for Abbott, Dexcom, Insulet, Medtronic, Sequel and Tandem.
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