Combination therapy shows promise to treat a rare, catastrophic pediatric brain cancer

Combination therapy shows promise to treat a rare, catastrophic pediatric brain cancer

[ad_1] St. Jude Children’s Research Hospital scientists identified a promising combination approach to treat a rare, but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT). Reactivating and maintaining p53, a protein responsible for tumor suppression, using the drugs idasantulin and selinexor, respectively, was well-tolerated, reduced tumor burden and increased survival in a laboratory…

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Genetic differences in surfactant proteins influence retinopathy of prematurity risk

Genetic differences in surfactant proteins influence retinopathy of prematurity risk

[ad_1] A new study from the University of Oklahoma suggests that small genetic differences in two proteins – previously known for their role in premature infants’ lungs – may also influence how their eyes develop, potentially affecting the risk of retinopathy of prematurity (ROP). ROP is a serious eye disease that affects premature infants, whose…

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Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments

Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments

[ad_1] A new multi-site study led by researchers at CU Anschutz shows that people with cystic fibrosis (CF) who start the triple-drug therapy elexacaftor/tezacaftor/ivacaftor (ETI) can safely reduce many of their daily lung treatments while maintaining good health for years. The study was published today in the Journal of Cystic Fibrosis. “This is incredibly meaningful…

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University of Iowa research finds an effective therapy for rare kidney disease in children

University of Iowa research finds an effective therapy for rare kidney disease in children

[ad_1] A rare and life-threatening kidney disease in children finally has an effective therapy, thanks in large part to pioneering research and clinical leadership from University of Iowa Health Care Stead Family Children’s Hospital.  The disease, known as C3 glomerulopathy (C3G), is an ultra-rare condition that primarily affects children and young adults. Only around 5,000 Americans have…

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Kennedy sharpens vaccine attacks, without scientific backing

Kennedy sharpens vaccine attacks, without scientific backing

[ad_1] As the federal government prepares for the next meeting of its Advisory Committee on Immunization Practices, Health and Human Services Secretary Robert F. Kennedy Jr. has intensified his attacks on aluminum vaccine components used in many shots to boost the body’s immune response. Kennedy, a longtime anti-vaccine activist before seeking public office, claims that…

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