Combination therapy shows promise to treat a rare, catastrophic pediatric brain cancer

Combination therapy shows promise to treat a rare, catastrophic pediatric brain cancer

[ad_1] St. Jude Children’s Research Hospital scientists identified a promising combination approach to treat a rare, but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT). Reactivating and maintaining p53, a protein responsible for tumor suppression, using the drugs idasantulin and selinexor, respectively, was well-tolerated, reduced tumor burden and increased survival in a laboratory…

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Study reveals significant financial strain on families seeking mental healthcare

Study reveals significant financial strain on families seeking mental healthcare

[ad_1] Behavioral health care has surged to represent 40 % of all medical expenditures for U.S. children in 2022, nearly doubling from 22 % in 2011, according to a new study published in JAMA Pediatrics. Researchers found that pediatric behavioral health expenditures totaled $41.8 billion in 2022, with families paying $2.9 billion out-of-pocket. Most concerning,…

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Community swimming program for Black youth boosts skills, sense of belonging, study finds

Community swimming program for Black youth boosts skills, sense of belonging, study finds

[ad_1] Black youth in the United States disproportionately experience fatal drowning at rates up to five times higher than their White peers. These statistics relate to historical and structural barriers Black youth face in learning to swim. In efforts to overcome these inequities, an innovative summer swimming program in Evanston, IL, was offered to Black…

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Genetic differences in surfactant proteins influence retinopathy of prematurity risk

Genetic differences in surfactant proteins influence retinopathy of prematurity risk

[ad_1] A new study from the University of Oklahoma suggests that small genetic differences in two proteins – previously known for their role in premature infants’ lungs – may also influence how their eyes develop, potentially affecting the risk of retinopathy of prematurity (ROP). ROP is a serious eye disease that affects premature infants, whose…

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Caring for Kids with Cancer

Caring for Kids with Cancer

[ad_1] Charlotte Musgrove: A journey in pediatric cancer nursing Charlotte Musgrove has carved out an impactful career in pediatric nursing at Stanford Medicine Children’s Health. With a mother who works at the renowned Mayo Clinic, she found inspiration close to home. During her senior year of college, Musgrove realized her desire to engage more directly…

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Study offers a unified biological model to explain the causes of autism

Study offers a unified biological model to explain the causes of autism

[ad_1] A new University of California San Diego School of Medicine study offers a unified biological model to explain how genetic predispositions and environmental exposures converge to cause autism spectrum disorder (ASD). The study, published in Mitochondrion on Dec. 9, 2025, describes a “three-hit” metabolic signaling model that reframes autism as a treatable disorder of…

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