Study reveals early mandibular catch-up growth in infants with Robin sequence

Study reveals early mandibular catch-up growth in infants with Robin sequence

Robin sequence is characterized by micrognathia, glossoptosis, and often cleft palate, leading to airway obstruction and feeding challenges. Treatment strategies vary widely, ranging from conservative interventions like prone positioning and specialized feeding therapy to surgical approaches such as mandibular distraction. However, whether early treatment influences long-term jaw growth remains debated, partly due to limited longitudinal…

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Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators. The findings are poised to redirect lupus research and open the door to more precise therapies that avoid broad immune…

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Researchers uncover a new way to understand how children fare after liver transplantation

Researchers uncover a new way to understand how children fare after liver transplantation

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered a new way to understand how children fare after liver transplantation: by focusing not on medical test results, but on how differently parents and children perceive the child’s well-being. The findings, published in The Journal of Pediatrics, come from the first multisite prospective…

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Kennedy sharpens vaccine attacks, without scientific backing

Kennedy sharpens vaccine attacks, without scientific backing

As the federal government prepares for the next meeting of its Advisory Committee on Immunization Practices, Health and Human Services Secretary Robert F. Kennedy Jr. has intensified his attacks on aluminum vaccine components used in many shots to boost the body’s immune response. Kennedy, a longtime anti-vaccine activist before seeking public office, claims that aluminum…

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Scientists uncover genetic components linked to bone density in young people

Scientists uncover genetic components linked to bone density in young people

Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and adolescents. This information could help identify pediatric patients who may benefit from strategies to help improve their bone health at an early age, helping them maintain healthy bones and prevent fractures in adulthood. Many children experience fractures…

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Focused ultrasound can be safely used in children being treated for brain cancer

Focused ultrasound can be safely used in children being treated for brain cancer

Columbia University researchers are the first to show that focused ultrasound – a non-invasive technique that uses sound waves to enhance the delivery of drugs into the brain – can be safely used in children being treated for brain cancer.  The focused ultrasound technique, developed by Columbia engineers, was tested in combination with chemotherapy in three children with diffuse midline glioma, a rare and aggressive brain cancer that is universally fatal.  The study found that focused ultrasound successfully opened the…

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Expert panel recommends new antibiotic strategies for resistant Bordetella pertussis

Expert panel recommends new antibiotic strategies for resistant Bordetella pertussis

Pertussis, or whooping cough, remains a highly contagious respiratory infection caused by Bordetella pertussis. Despite inclusion of pertussis vaccines in immunization programs since the 1970s, outbreaks have re-emerged globally due to waning immunity and bacterial evolution. In China, cases have dramatically increased since 2017, with more than 400,000 reported between January and July 2024. Meanwhile,…

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