Year-long adherence to buprenorphine sharply reduces overdose risk in young people

Year-long adherence to buprenorphine sharply reduces overdose risk in young people

New research from Mass General Brigham finds that adolescents and young adults who stayed on the medication buprenorphine for at least a year had markedly lower risks of opioid overdose and hospitalization compared with peers who discontinued medication early or took it inconsistently. The results, published in Pediatrics, are especially relevant as youth overdose death…

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Updated CPR guidelines provide expanded recommendations for managing choking and opioid overdose

Updated CPR guidelines provide expanded recommendations for managing choking and opioid overdose

The “2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC),” published today in the Association’s flagship journal, Circulation, marks the first full revision of lifesaving resuscitation guidance since 2020. Among the updates are expanded recommendations for managing choking and suspected opioid overdose, in addition to other lifesaving interventions. Each year,…

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Buprenorphine treatment produces greatest health gains and cost savings for mothers and infants

Buprenorphine treatment produces greatest health gains and cost savings for mothers and infants

Over the last 20 years, substance use-related deaths have more than doubled for women of reproductive age. Overdose deaths are now a leading cause of maternal mortality in the U.S., and in some states, the leading cause. Still, substantial gaps remain in understanding how different treatment approaches influence the short- and long-term health of mothers…

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Polysubstance-involved opioid overdoses found to be prevalent among youth

Polysubstance-involved opioid overdoses found to be prevalent among youth

Most research suggests that opioid overdoses involving multiple substances in the United States typically occur among people ages 25-54. However, a new study led by Boston University School of Public Health (BUSPH) and Mass General Brigham for Children indicates that polysubstance-involved opioid overdoses are also prevalent among youth. Published in the journal Pediatrics, the study…

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