Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

[ad_1] Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators. The findings are poised to redirect lupus research and open the door to more precise therapies that avoid broad…

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Prior exposure to cold viruses boosts antibody response against SARS-CoV-2

Prior exposure to cold viruses boosts antibody response against SARS-CoV-2

[ad_1] Prior exposure to coronaviruses that cause ordinary colds can boost the immune system’s ability to attack a vulnerable site on the COVID-19-causing coronavirus SARS-CoV-2, according to a study led by investigators at Weill Cornell Medicine. The finding suggests a new vaccination strategy that might provide broader and more durable protection against SARS-CoV-2 strains compared…

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Updated guidelines published for pediatric CPR and emergency cardiovascular care

Updated guidelines published for pediatric CPR and emergency cardiovascular care

[ad_1] The American Academy of Pediatrics and the American Heart Association (the Association), a relentless force changing the future of health for everyone everywhere, have published updated guidelines for cardiopulmonary resuscitation and emergency cardiovascular care for newborn and pediatric populations. The “2025 American Heart Association and American Academy of Pediatrics Guidelines for Cardiopulmonary Resuscitation and…

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Updated CPR guidelines provide expanded recommendations for managing choking and opioid overdose

Updated CPR guidelines provide expanded recommendations for managing choking and opioid overdose

[ad_1] The “2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC),” published today in the Association’s flagship journal, Circulation, marks the first full revision of lifesaving resuscitation guidance since 2020. Among the updates are expanded recommendations for managing choking and suspected opioid overdose, in addition to other lifesaving interventions. Each…

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Mother’s voice promotes development of language pathways in preemies’ brains

Mother’s voice promotes development of language pathways in preemies’ brains

[ad_1] Hearing the sound of their mother’s voice promotes development of language pathways in a premature baby’s brain, according to a new Stanford Medicine-led study. During the study, which is publishing online Oct. 13 in Frontiers in Human Neuroscience, hospitalized preemies regularly heard recordings of their mothers reading to them. At the end of the…

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Researchers develop a powerful new tool to sharpen the accuracy of genetic testing

Researchers develop a powerful new tool to sharpen the accuracy of genetic testing

[ad_1] Researchers at Texas Children’s Neurological Research Institute (NRI) and Baylor College of Medicine have developed a powerful new tool within the Genome Aggregation Database (gnomAD) to sharpen the accuracy of genetic testing – a breakthrough with direct implications for patient diagnoses and care worldwide. The work, published in Nature Communications, applies a method called…

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Simple tools increase pediatrician compliance with early peanut allergy prevention guidelines

Simple tools increase pediatrician compliance with early peanut allergy prevention guidelines

[ad_1] A few easy-to-implement tools – a training video, electronic health record prompts and handouts for families – greatly increased how often pediatricians recommended early peanut introduction to infants, reports a new clinical study led by Northwestern University and Ann & Robert H. Lurie Children’s Hospital of Chicago. Since 2017, national guidelines have encouraged pediatricians…

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