[ad_1] A new University of California San Diego School of Medicine study offers a unified biological model to explain how genetic predispositions and environmental exposures converge to cause autism spectrum disorder (ASD). The study, published in Mitochondrion on Dec. 9, 2025, describes a “three-hit” metabolic signaling model that reframes autism as a treatable disorder of…
[ad_1] Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete. People may forget what they took, use over-the-counter drugs, take leftover prescription drugs, buy medicines online, or be exposed unintentionally through food and the environment. As…
[ad_1] A team of researchers at the Icahn School of Medicine at Mount Sinai has uncovered why children with the same leukemia-causing gene mutation can have dramatically different outcomes: it depends on when in development the mutation first occurs. The study, led by Elvin Wagenblast, PhD, Assistant Professor of Oncological Sciences, and Pediatrics, at the…
[ad_1] In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received chemotherapy-based conditioning or total body irradiation (TBI), the standard conditioning regimen used before hematopoietic cell transplantation. The findings could allow more patients to avoid TBI and its…
[ad_1] Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a new study. The study included over 1,000 patients, representing the largest and most comprehensive analysis of long-term transplant outcomes to…
[ad_1] For the first time in 20 years, the U.S. has recorded homegrown malaria cases. The country sees about 2,000–2,500 malaria cases each year linked to travel to malaria-endemic areas such as sub-Saharan Africa and parts of South America and Southeast Asia—but the nine locally transmitted cases seen so far this year were contracted by…
[ad_1] A genetic variant is likely putting some children suffering with myocarditis – inflammation of the heart muscle – at higher risk of developing heart failure, which can be fatal, according to a study published today in Circulation Heart Failure. According to the study, 34.4% of the children who developed dilated cardiomyopathy after developing myocarditis…
[ad_1] A new USC study shows teens with higher blood levels of per- and polyfluoroalkyl substances (PFAS) measured before bariatric surgery had smaller improvements in blood sugar over five years, including fasting glucose and hemoglobin A1c (HbA1c), which measures average blood sugar levels over the past 60-90 days. Blood sugar is a key marker of…
[ad_1] A new multi-site study led by researchers at CU Anschutz shows that people with cystic fibrosis (CF) who start the triple-drug therapy elexacaftor/tezacaftor/ivacaftor (ETI) can safely reduce many of their daily lung treatments while maintaining good health for years. The study was published today in the Journal of Cystic Fibrosis. “This is incredibly meaningful…
[ad_1] A rare and life-threatening kidney disease in children finally has an effective therapy, thanks in large part to pioneering research and clinical leadership from University of Iowa Health Care Stead Family Children’s Hospital. The disease, known as C3 glomerulopathy (C3G), is an ultra-rare condition that primarily affects children and young adults. Only around 5,000 Americans have…