Advances in hemophilia gene therapy bring hope for pediatric patients

Advances in hemophilia gene therapy bring hope for pediatric patients

[ad_1] In the past three years, gene therapy has reshaped what’s possible in hemophilia treatment for patients 18 and older. But a key question remains: How soon will these advances reach children? At the 2025 American Society of Hematology (ASH) Annual Meeting, international hemophilia expert Guy Young, MD, Director of the Hemostasis and Thrombosis Center in the Cancer and…

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Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL

Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL

[ad_1] In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received chemotherapy-based conditioning or total body irradiation (TBI), the standard conditioning regimen used before hematopoietic cell transplantation. The findings could allow more patients to avoid TBI and its…

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New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease

New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease

[ad_1] Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a new study. The study included over 1,000 patients, representing the largest and most comprehensive analysis of long-term transplant outcomes to…

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Digital tools and chatbots can expand genetic counseling for young cancer survivors

Digital tools and chatbots can expand genetic counseling for young cancer survivors

[ad_1] A groundbreaking new study from the Alliance for Clinical Trials in Oncology aims to test whether digital tools and chatbot technology can help young adult cancer survivors get the genetic counseling they need to better understand future health risks to themselves and family members. Led by Alliance Study Chair Angela Bradbury, MD, Professor of Medicine…

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