December 30, 2025
Headlines

bone marrow

Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL

Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL

DRRA04 mins

In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received chemotherapy-based conditioning or total body irradiation (TBI), the standard conditioning regimen used before hematopoietic cell transplantation. The findings could allow more patients to avoid TBI and its associated…

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New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease

New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease

DRRA05 mins

Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a new study. The study included over 1,000 patients, representing the largest and most comprehensive analysis of long-term transplant outcomes to date…

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Experimental gene therapy restores immune system function in children with genetic immune disorder

Experimental gene therapy restores immune system function in children with genetic immune disorder

DRRA06 mins

An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has restored and maintained immune system function in 59 of 62 children born with ADA-SCID, a rare and deadly genetic immune disorder. Severe combined immunodeficiency due to adenosine deaminase deficiency, or ADA-SCID, is caused by mutations in the ADA…

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