[ad_1] An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has restored and maintained immune system function in 59 of 62 children born with ADA-SCID, a rare and deadly genetic immune disorder. Severe combined immunodeficiency due to adenosine deaminase deficiency, or ADA-SCID, is caused by mutations in the…
[ad_1] Pertussis, or whooping cough, is on the rise and incidence now exceeds pre-pandemic numbers. While in adults and older children the cough can be bothersome and last for months, pertussis in young infants can be life-threatening. Most children under 2 months of age with pertussis in the United States are hospitalized. In a special…
[ad_1] Children and adolescents were twice as likely to experience long COVID after catching COVID for the second time, compared to their peers with a single previous infection, according to a large study funded by the National Institutes of Health (NIH) and published in Lancet Infectious Diseases. These results run counter to the popular perceptions…
[ad_1] The Family Heart Foundation, a leading research and advocacy organization, announced the online publication of recommendations from a multidisciplinary panel in the Journal of Pediatrics to promote the early identification of children living with familial hypercholesterolemia (FH). A common life-threatening genetic condition that causes high cholesterol from birth, FH can lead to premature heart…
[ad_1] A research collaboration involving scientists and students at The University of Texas at Dallas has found a clear connection between chronic sickle cell disease pain and the bacteria present in the gastrointestinal tract. Dr. Katelyn Sadler, assistant professor of neuroscience in the School of Behavioral and Brain Sciences, is the corresponding author of the study, which was conducted…
[ad_1] A new study has found that prompt administration of opioid pain relief in emergency departments reduces the likelihood of hospitalization for children with sickle cell disease, according to findings published in JAMA Pediatrics. Sickle cell disease (SCD) is a genetic blood disorder that can cause severe episodes of intense pain due to blocked blood flow. While national…
[ad_1] Cardiac arrest happens when the heart stops pumping blood properly, cutting off oxygen to the brain and other vital organs. In these emergencies, cardiopulmonary resuscitation (CPR) can help keep blood and oxygen moving until medical help arrives. For children, CPR usually needs both chest compressions and rescue breaths, because many cases are caused by…
[ad_1] Blood pressure matters at all ages. Children with higher blood pressure at age 7 may be at an increased risk of dying of cardiovascular disease by their mid-50s, according to preliminary research presented at the American Heart Association’s Hypertension Scientific Sessions 2025. The meeting is in Baltimore, September 4-7, 2025, and is the premier scientific exchange focused…
[ad_1] Children with sickle cell disease are more likely to have dental problems – but fewer than half of those covered by Michigan Medicaid got dental care in 2022, according to a new study. The findings, led by Michigan Medicine and non-profit RAND Corporation, appear in JAMA Network Open. Sickle cell disease is known…
[ad_1] COVID-19 prevention methods such as masking and social distancing also suppressed the circulation of common respiratory diseases, leaving young children lacking immunity to pathogens they otherwise would have been exposed to, a new multi-center clinical research study reveals. The investigators say their findings help explain the large post-pandemic rebound in these diseases and enable…