Recent advances in CAR-NK cell therapy could revolutionze cancer treatment

Recent advances in CAR-NK cell therapy could revolutionze cancer treatment

[ad_1] Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, manufacturing complexity, and limited effectiveness against solid tumors. CAR-T cell therapy, while highly effective in certain blood cancers, is frequently associated with cytokine release syndrome, neurotoxicity, and prolonged production timelines. These challenges highlight the need for alternative immune cell…

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Forever chemicals linked to higher liver disease risk in adolescents

Forever chemicals linked to higher liver disease risk in adolescents

[ad_1] A new study co-led by the Southern California Superfund Research and Training Program for PFAS Assessment, Remediation and Prevention (ShARP) Center and the University of Hawai’i has linked certain common “forever chemicals” to a higher risk of liver disease in adolescents. These synthetic compounds, known as per- and polyfluoroalkyl substances (PFAS), may as much as triple the chances…

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Advances in hemophilia gene therapy bring hope for pediatric patients

Advances in hemophilia gene therapy bring hope for pediatric patients

[ad_1] In the past three years, gene therapy has reshaped what’s possible in hemophilia treatment for patients 18 and older. But a key question remains: How soon will these advances reach children? At the 2025 American Society of Hematology (ASH) Annual Meeting, international hemophilia expert Guy Young, MD, Director of the Hemostasis and Thrombosis Center in the Cancer and…

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Genetic differences in surfactant proteins influence retinopathy of prematurity risk

Genetic differences in surfactant proteins influence retinopathy of prematurity risk

[ad_1] A new study from the University of Oklahoma suggests that small genetic differences in two proteins – previously known for their role in premature infants’ lungs – may also influence how their eyes develop, potentially affecting the risk of retinopathy of prematurity (ROP). ROP is a serious eye disease that affects premature infants, whose…

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Online reference library provides a more accurate picture of drug exposure

Online reference library provides a more accurate picture of drug exposure

[ad_1] Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete. People may forget what they took, use over-the-counter drugs, take leftover prescription drugs, buy medicines online, or be exposed unintentionally through food and the environment. As…

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Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL

Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL

[ad_1] In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received chemotherapy-based conditioning or total body irradiation (TBI), the standard conditioning regimen used before hematopoietic cell transplantation. The findings could allow more patients to avoid TBI and its…

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