Let’s talk quickly about Nalbuphine, the Diet Coke of opioids. mechanism Most opioids are basic. They’re pure μ-opioid agonists. Nalbuphine is more complex, with a multimodal mechanism of action. Key effects include: [#1] Partial agonism at μ-opioid receptors: Nalbuphine functions as a partial μ-agonist, similar to buprenorphine. Compared to buprenorphine, nalbuphine seems to stimulate the […]
