[ad_1]
November 25, 2025
2 min read
Key takeaways:
- Patients with a nutrition consultation had a significantly higher average mature oocyte yield per oocyte retrieval.
- Multiple nutrition consultations were tied to even higher odds of obtaining mature oocytes.
Nutrition counseling, especially across multiple consultations, improved IVF outcomes, according to an analysis presented at the ASRM Scientific Congress & Expo.
Andres Reig, MD, an attending physician at Reproductive Medical Associates in Basking Ridge, New Jersey, told Healio that obesity and overweight “have been linked with poor pregnancy and reproductive outcomes, with numerous studies evaluating the association between increased weight, BMI or different body compositions on pregnancy health and neonatal outcomes.”
Patients with a nutrition consultation had a significantly higher average mature oocyte yield per oocyte retrieval. Image: Adobe Stock
“Similarly, many studies have analyzed the relationship between these issues and the outcomes of IVF cycles, with mixed results,” he added. “However, we found no research evaluating the impact of counseling from a registered dietician and nutritionist (RDN) on the outcomes of ovarian stimulation and the subsequent IVF process.”
Reig and colleagues assessed 3,919 IVF cycles from 2,440 patients — of whom 1,125 received RDN counseling — to determine differences in outcomes like the numbers of mature oocytes (MII), useable blastocysts and euploid embryos.
Among those receiving RDN counseling, 56.6% had one consult and 43.4% participated in additional counseling.
The researchers reported that patients with RDN counseling had a significantly higher average MII yield per oocyte retrieval than those patients without consultation (10.3 vs. 8.8). They noted the difference remained when they evaluated euploid embryos (2.9 vs. 2.8) and usable blastocysts (4.1 vs. 3.7).
“Importantly, that improvement was modest — about one euploid embryo more on average than patients without nutritional counseling — but this small improvement could mean an additional attempt at a euploid embryo transfer, which carries a 60% to 65% success rate at our institution,” Reig told Healio.
Reig and colleagues also found that participants with more than one RDN consultation had higher odds of obtaining MII oocytes (adjusted OR = 2.33; 95% CI, 1.04-5.21) and usable blastocysts (aOR = 1.66; 95% CI, 1.04-2.65).
Andres Reig
“In an attempt to isolate the effect of the RDN counseling, we also evaluated a subset of about 120 patients who had undergone two IVF cycles, one before and one after the RDN consult, and the results continued to show improved outcomes in those with RDN counseling,” Reig said.
He said that while the study “does not serve to clarify the reasons behind the improvement, which could be related to the nutrition counseling and interventions themselves or to the fact that more health-conscious patients are more likely to undergo this counseling to begin with, it does highlight the importance of a healthy lifestyle when trying to conceive, in particular via IVF.”
Reig concluded that for future research, “studying specific dietary interventions and lifestyle modifications and which are the most helpful for which patients is the logical next step, which could in turn lead to personalized recommendations that take each patient’s individual aspects into account to optimize their outcome.”
For more information:
Andres Reig, MD, can be reached at primarycare@healio.com.
Sources/Disclosures
Source:
Reig A, et al. O-57. Presented at: ASRM Scientific Congress & Expo; Oct. 25-29, 2025; San Antonio.
Disclosures:
Healio could not determine relevant financial disclosures at the time of publication.
Ask a clinical question and tap into Healio AI’s knowledge base.
- PubMed, enrolling/recruiting trials, guidelines
- Clinical Guidance, Healio CME, FDA news
- Healio’s exclusive daily news coverage of clinical data
[ad_2]
Source link
