#3: Twice is Nice? Cephalexin BID for UTI
Spoon Feed —
In this retrospective study of ED-diagnosed UTIs, Cephalexin dosed twice daily was just as effective as four times daily, with no significant difference in treatment failure – suggesting BID dosing may be a practical, adherence-friendly option in some patients.
Source
Cephalexin twice daily versus four times daily for the treatment of urinary tract infections diagnosed in the emergency department. Am J Emerg Med. 2025 Jul;93:80-85. doi: 10.1016/j.ajem.2025.03.058. Epub 2025 Mar 24. PMID: 40184663
