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In this episode I first suggest you take a look at the recently published (ahead of print) VANCS study on the use of vasopressin as a sole agent in the treatment of vasoplegic shock. Then I review the reasons never to use sodium bicarbonate in lactic acidosis.
CME: https://earnc.me/3CX3ha
The Vancs study: https://www.ncbi.nlm.nih.gov/pubmed/27841822
The two articles I recommend on bicarb:
Forsythe: https://www.ncbi.nlm.nih.gov/pubmed/10631227
Sabatini: https://www.ncbi.nlm.nih.gov/pubmed/18322160
Outline by Brian Park: Outline