
ICARUS ED Trial: Concentrated Albumin for Undifferentiated Sepsis in the Emergency Department
🧭 REBEL Rundown 📌 Key Points 🩸 No BP Boost at 24h: Early 20% albumin in sepsis didn’t significantly improve systolic BP at 24 hours compared to standard care. 💉 Less Fluid, Fewer Pressors: Albumin group received 725mL less fluid over 72h and needed vasopressors 7.4% less often—but the differences were small and statistically fragile….