This is the eighth in a series of blog posts on new research in emergency toxicology. The last post was about nitazenes and can be found here. We deal with all sorts of poisons here in Virchester, so be prepared for anything. Hydrofluoric acid (HFA) is a corrosive substance used widely in industry and occasionally…
Let’s talk quickly about Nalbuphine, the Diet Coke of opioids. mechanism Most opioids are basic. They’re pure μ-opioid agonists. Nalbuphine is more complex, with a multimodal mechanism of action. Key effects include: [#1] Partial agonism at μ-opioid receptors: Nalbuphine functions as a partial μ-agonist, similar to buprenorphine. Compared to buprenorphine, nalbuphine seems to stimulate the…
🧭 REBEL Rundown 📌 Key Points 🫁💨 Nebulized TXA stops bleeding faster! 72% of ED patients had cessation at 30 min vs 51% with IV TXA. 📉🏥 Fewer procedures needed: Neb TXA patients had lower rates of bronchial artery embolization (25% vs 47%). 🌬️💊 Easy to use: Neb TXA is cheap, non-invasive, doesn’t require an…
Cite this article as: Morgenstern, J. The continuing quest to treat numbers, not patients (OPTRESS), First10EM, September 8, 2025. Available at:https://doi.org/10.51684/FIRS.143446 Might elderly patients, with a higher risk of undiagnosed hypertension and higher rates of vascular disease, require higher blood pressure targets in sepsis? Or might this just be yet another example of medicine…
We’re super excited about coming to NYC, but even more about unleashing The VExUS Course 2.0, which will include the integration of venous congestion into our comprehensive hemodynamic interface framework. So participants will have an all-new version of the course, along with an introduction to the interface concept which is gaining a lot of traction,…
Cases Case 1: “Maybe it’s not just a broken bone” A 50-year-old female presents to the ED with complaints of right ankle pain after a witnessed mechanical slip and fall. She is brought into intake and as part of the new triage protocol at your hospital, she is asked the Single Alcohol Screening Question and…
Cases Case 1: “Maybe it’s not just a broken bone” A 50-year-old female presents to the ED with complaints of right ankle pain after a witnessed mechanical slip and fall. She is brought into intake and as part of the new triage protocol at your hospital, she is asked the Single Alcohol Screening Question and…
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast Episode 316: Keywords Part 31: Airway Anatomy and Pharmacology with Tym Kajstura Play Episode Pause Episode Mute/Unmute Episode Rewind 10 Seconds 1x Fast Forward 10 seconds 00:00 / Subscribe Share Source link
Authors: Jon Chastek, DO (EM Resident Physician, UMass Chan Medical School); Cassandra Mackey, MD (Assistant Professor of Emergency Medicine, UMass Chan Medical School) // Reviewed by: Sophia Görgens, MD (EM Physician, BIDMC, MA); Alex Koyfman, MD (@EMHighAK); Brit Long, MD (@long_brit) Welcome to EM@3AM, an emDOCs series designed to foster your working knowledge by providing…
A 40-year-old female presents to the ED obtunded and diaphoretic. She is accompanied by her husband. Point of care (POC) glucose reveals a blood sugar of 40 mg/dL. An amp of D50 is ordered and collateral history is obtained from the husband. He states that the patient has felt nauseous for the past 24 hours…