18 Best Hand Soaps for Eczema 2025, According to Derms

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Have you ever washed your hands and thought to yourself, “Why do my hands feel even drier than before?” We’ve probably all been there and done that, but imagine this uncomfortable, tight feeling on your skin when you’re also dealing with eczema—a true nightmare for those with a compromised skin barrier. If you have this skin condition and your hands get it the worst, it’s time to spend your coin on hand soaps for eczema that are actually formulated to soothe dry, itchy skin. Because the last thing your hands need is a cupcake-scented, bright pink goop.

Best Hand Soaps for Eczema at a Glance

But where does one even begin with finding the best hand soaps for eczema? Let’s start with the pros, like dermatologists, who have a wealth of insight into this skin condition. We got Dr. Tiffany J. Libby, a Mohs Surgeon and board-certified dermatologist, Dr. Diane Alexander, president and founder of Artisan, Dr. Kristina Collins, a board-certified dermatologist specializing in Mohs micrographic surgery, and Dr. Peter Bittar, dermatologist and Mohs Surgeon at Miami Dermatology & Laser Institute, on hand (no pun intended) to answer all of your questions about eczema.

Answers are one thing, but you’re going to need product recommendations to see any positive changes, so our experts have done you a solid and shared the best hand soaps for eczema, too. Without further ado, let’s get into it.

What is eczema?

“Eczema is a chronic inflammatory skin condition that presents as pink to red-brown rough patches of skin that are often dry, itchy, and irritated,” explains Dr. Libby, adding, “It is believed to be influenced by a combination of genetic, environmental, and immune system factors.”

Why should I use a hand soap for eczema? 

It’s simple: You have a compromised skin barrier that is more likely to experience dryness and irritation. To counteract these side effects, fill your hand soap jar with a formula that’s specially made for eczema. This is going to look like nourishing, hydrating, soothing ingredients that’ll assist with restoring and repairing the skin’s moisture barrier.

What ingredients should I look for in a hand soap for eczema? 

Colloidal oatmeal, glycerin, hyaluronic acid, ceramides, shea butter, allantoin, and niacinamide are going to become your best friends during your search for the best hand soap for eczema. They’ll help transform your skin from rough, dry, itchy, and inflamed into healthy, smooth, soft, and moisturized.

What ingredients should I avoid in a hand soap for eczema?

Don’t even think about buying a hand soap that contains fragrance, harsh dyes, essential oils, exfoliating beads, or acids like salicylic acid or glycolic acid. These ingredients will likely only worsen your eczema.

Now that you know the dos and don’ts of hand soaps for eczema, here are the best gentle, derm-approved formulas that your skin will absolutely love.

What else should I do to help my eczema?

While eczema might seem like a topical concern, it goes much deeper. “As a physician, I’ve learned that the inflammation we see on our skin often mirrors what’s happening inside our bodies,” says Dr. Alexander. “For people with sensitive or eczema-prone skin, it’s essential to avoid inflammatory triggers in both your diet and your skin care, because certain foods and harsh chemicals in soaps can trigger inflammation and lead to flare-ups. I’ve also seen that improving your gut health (i.e., eating probiotic-rich foods) can sometimes improve skin health.”

Best Eczema-Friendly Hand Soaps to Shop Now, According to Derms



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