Digital Expression Control with GPEx® Lightning: Enabling Complex Biologics in CHO Cells

Digital Expression Control with GPEx® Lightning: Enabling Complex Biologics in CHO Cells


This scientific poster showcases how GPEx® Lightning enables precise, digital control of gene expression for complex biologics. By leveraging targeted integration into ~200 Dock sites and a single optimized construct, developers can fine-tune gene ratios for co-expression of enzymes, cofactors, and multi-chain proteins. Learn how this approach streamlines screening, boosts titers, and shortens timelines—even for products with unknown stoichiometry.



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